Running the program: Once the program is launched, change the parameter values or use the default, and then click the "Initialize" button, which becomes "Start" after clicking. Then hit the "Start" button to run the simulation. The graphics are updated every 0.2 seconds. Several windows will pop up once the simulation is started:
Actin cables with For3p dots: snapshot showing actin concentration along four randomly chosen cables, together with the For3p associtated along the actin cables. Click on a lattice site to see the values of the field corresponding to each lattice site.
For3p dimers in cytoplasm: snapshot showing discrete For3p dimers in a 2D slice at the center of the cell. Click on a lattice site to see the values of the field corresponding to each lattice site.
Actin in cytoplasm: snapshot of actin monomer concentration in the cytoplasm in a 2D slice at the center of the cell. Click on a lattice site to see the values of the field corresponding to each lattice site.
Actin density in cytoplasm: time averaged actin concentration profile along the long axis of the cell.
Tip For3p for different cables: four curves showing the number of For3p dimers associated with four randomly chosen cable tips, as a function of time.
More options are available in the parameter file "init.dat". To make use of this parameter file, download the jar file, and double click (or type "java -jar actinCable.jar" in a terminal window) to launch the program. Upon clicking the
"Initialize" button, a directory "actinData" containing the file "init.dat" will be created in the same directory as the jar file. Use a text editor to open init.dat and change the values of the parameters (e.g., true to false). Save the init.dat file and click New->Reset, or launch the program again in order for the new parameters to take effect.
This project used the Open Source Physics (OSP) library for graphics and user control.
Updated Apr 9, 2008.