Book Chapters

Peer Reviewed Journal Articles

Peer Reviewed Conference Proceedings

Views/Opinion Articles


  1. T. Drake, E. Yusuf and D. Vavylonis, "A Systems-Biology Approach to Yeast Actin Cables", in "Advances in Systems Biology", Springer series Advances in Experimental Medicine and Biology, 736:325-35 (2012).


  1. L. M. McMillen and D. Vavylonis, "Model of turnover kinetics in the lamellipodium: implications of slow- and fast- diffusing capping protein and Arp2/3 complex," PHYSICAL BIOLOGY 13:066009 (2016).
  2. L. Merlini, B. Khalili, F. O. Bendez˙, D. Hurwitz, V. Vincenzetti, D. Vavylonis, S. M. Martin, "Local pheromone release from dynamic polarity sites underlies cell-cell pairing during yeast mating," CURRENT BIOLOGY 26:1117-1125 (2016).
  3. D. Zhang, T. C. Bidone, D. Vavylonis, "ER-PM contacts define actomyosin kinetics for proper contractile ring assembly," CURRENT BIOLOGY 26:647-653 (2016).
  4. H. Tang, T. C. Bidone, D. Vavylonis, "Computational model of polarized actin cables and contractile actin ring formation  in budding yeast," CYTOSKELETON, 72: 517-533 (2015).
  5. D. B. Heisler, E. Kudryashova, D. O. Grinevich, C. Suarez, J. D. Winkelman, K. G. Birukov, S. R. Kotha, N. L. Parinandi, D. Vavylonis, D. R. Kovar, D. S. Kudryashov, "ACD toxin-produced actin oligomers poison formin-controlled actin polymerization," SCIENCE, 49:535-539 (2015).
  6. T. Xu, D. Vavylonis, F.-C. Tsai, G. H. Koenderink, W. Nie, E. Yusuf, I-J. Lee, J.-Q. Wu, X. Huang, "SOAX: A software for quantification of 3D biopolymer networks," SCIENTIFIC REPORTS, 5:9081 (2015).
  7. E. Vitriol, L. M. McMillen, M. Kapustina, S. Gomez, D. Vavylonis, and J. Q. Zheng, "Two Functionally Distinct Sources of Actin Monomers Supply the Leading Edge of Lamellipodia," CELL REPORTS  11:433-445 (2015).
  8. F. O. Bendez˙, V. Vincenzetti, D. Vavylonis, R. Wyss, H. Vogel, and S. G. Martin, "Spontaneous Cdc42 Polarization Independent of GDI-mediated Extraction and Actin-based Trafficking,"  PLOS BIOLOGY, 13:e1002097 (2015).
  9. W. Nie, M.-T. Wei, D. H. Ou Yang, S. S. Jedlicka, D. Vavylonis, "Formation of contractile networks and fibers in the medial cell cortex through myosin-II turnover, contraction, and stress-stabilization," CYTOSKELETON 72:29-46 (2015).
  10. T. C. Bidone, H. Tang, D. Vavylonis, "Dynamic Network Morphology and Tension Buildup  in 3D Model of Cytokinetic Ring Assembly," BIOPHYS. J. 107:2618-2628 (2014).
  11. H. Tang, D. Laporte and D. Vavylonis, "Actin cable distribution and dynamics arising from cross-linking, motor-pulling and filament turnover," MOL. BIOL. CELL 25:3006-3016 (2014) .
  12. S. Yamashiro, H. Mizuno, M. B. Smith, G. L. Ryan, T. Kiuchi, D. Vavylonis, N. Watanabe, "New single-molecule speckle microscopy reveals modification of the retrograde actin flow by focal adhesions at nanometer scales," MOL. BIOL. CELL 25:1010-1024 (2014).
  13. T. Xu, D. Vavylonis and X. Huang, "3D Actin Network Centerline Extraction with Multiple Active Contours," MEDICAL IMAGE ANALYSIS 18:272-284 (2014).
  14. T. Drake and D. Vavylonis, "Model of fission yeast cell shape driven by membrane-bound growth factors and the cytoskeleton," PLOS COMPUTATIONAL BIOLOGY, 9:e1003287 (2013).
  15. N. Watanabe, Y. Sawako, D. Vavylonis and T. Kiuchi, "Molecular viewing of actin polymerizing actions and beyond: combination analysis of SiMS microscopy with modeling, FRAP and s-FDAP," DEVELOPMENT, GROWTH AND DIFFERENTIATION, 55:508-514 (2013).
  16. M. B. Smith, T. Kiuchi, N. Watanabe and D. Vavylonis, "Distributed Actin Turnover in the Lamellipodium and FRAP Kinetics," BIOPHYS. J. 104:247-257 (2013).
  17. G. L. Ryan, N. Watanabe and D. Vavylonis, "Image Analysis Tools to Quantify Cell Shape and Protein Dynamics near the Leading Edge," CELL STRUCTURE AND FUNCTION, 19:1-7 (2013).
  18. D. Laporte, N. Ojkic, D. Vavylonis and J.-Q. Wu, "alpha-Actinin and fimbrin cooperate with myosin-II to organize actomyosin bundles during contractile-ring assembly," MOL. BIOL. CELL, 23:3094-3110 (2012).
  19. M. Das, T. Drake, D. Wiley, P. Buchwald, D. Vavylonis and F. Verde, "Oscillatory dynamics of Cdc42 GTPase in the control of polarized growth," SCIENCE 337:239-243 (2012).
  20. G. L. Ryan, N. Watanabe and D. Vavylonis, "A review of models of fluctuating protrusion and retraction patterns at the leading edge of motile cells," CYTOSKELETON 69:195-206 (2012) .
  21. G. L. Ryan, H. Petroccia, N. Watanabe and D. Vavylonis, "Excitable actin dynamics in lamellipodial protrusion and retraction," BIOPHYS. J. 102:1493-1502 (2012).
  22. M. B. Smith, E. Karatekin, A. Gohlke, H. Mizuno, N. Watanabe and D. Vavylonis, "Interactive, computer-assisted tracking of speckle trajectories in fluorescence microscopy: application to actin polymerization and membrane fusion," BIOPHYS. J., 101:1794-1804 (2011). (Evaluated in Faculty of 1000)
  23. N. Ojkic, J.-Q. Wu and D. Vavylonis, "Model of Myosin Node Aggregation into a Contractile Ring: the Effect of Local Alignment," J. PHYS.: CONDENS. MATTER special issue on Cooperative Dynamics in Cells, 23, 374103 (2011).
  24. M. B. Smith, H. Li, T. Shen, X. Huang, E. Yusuf, and D. Vavylonis, "Segmentation and Tracking of Cytoskeletal Filaments using Open Active
    Contours," CYTOSKELETON, 67 693-705 (2010).
  25. N. Ojkic and D. Vavylonis, "Kinetics of Myosin Node Aggregation into a Contractile Ring," PHYS. REV. LETT., 105 048102 (2010).
  26. T. Drake and D. Vavylonis, "Cytoskeletal Dynamics in Fission Yeast: A Review of Models for Polarization and Division," HFSP J., 4 122-130 (2010).
  27. H. Wang and D. Vavylonis, "Model of For3p-mediated actin cable assembly in fission yeast," PLOS ONE, 3 e4078 (2008).
  28. D. Vavylonis, J.-Q. Wu, S. Hao, B. O'Shaughnessy, and T. D. Pollard, "Assembly Mechanism of the Contractile Ring for Cytokinesis by
    Fission Yeast," 
    SCIENCE, 319 97-100 (2008). (Evaluated in Faculty of 1000)
  29. I. Fujiwara, D. Vavylonis, and T. D. Pollard, "Polymerization kinetics of ADP- and ADP-Pi-actin determined by TIRF microscopy," PROC. NATL. ACAD. SCI. USA, 104 8827-8832 (2007).
  30. D. Vavylonis, D. R. Kovar, B. O'Shaughnessy, and T. D. Pollard, "Model of Formin-Associated Actin Filament Elongation," MOLECULAR CELL, 39 455-466 (2006).
  31. D. Vavylonis, Q. Yang, and B. O'Shaughnessy, "Actin Polymerization Kinetics, Cap Structure, and Fluctuations", PROC. NATL. ACAD. SCI. USA 102, 8543-8548 (2005). (Evaluated in Faculty of 1000).
  32. B. O'Shaughnessy and D. Vavylonis, "Non-Equilibrium in Adsorbed Polymer Layers", J. PHYS.: CONDENS. MATTER 17, R63-R99 (2005).
  33. B. O'Shaughnessy and D. Vavylonis, "Dynamics of Living Polymers", EUR. PHYS. J. E 12, 481-496 (2003).
  34. B. O'Shaughnessy and D. Vavylonis, "The Slowly Formed Guiselin Brush", EUROPHYS. LETT. 63, 895-901 (2003).
  35. B. O'Shaughnessy and D. Vavylonis, "Irreversible Adsorption from Dilute Polymer Solutions", EUR. PHYS. J. E 11, 213-230 (2003).
  36. B. O'Shaughnessy and D. Vavylonis, "Pulsed Laser Polymerization at Low Conversions: Broadening and Chain Transfer Effects", MACROMOL. THEORY SIMUL. 12, 401-412 (2003). (Featured on cover).
  37. B. O'Shaughnessy and D. Vavylonis, "The Ultrasensitivity of Living Polymers", PHYS. REV. LETT. 90, 118301 (2003).
  38. B. O'Shaughnessy and D. Vavylonis, "Irreversibility and Polymer Adsorption", PHYS. REV. LETT. 90, 056103 (2003).
  39. B. O'Shaughnessy and D. Vavylonis, "Interfacial Reactions: Mixed Order Kinetics and Segregation Effects", PHYS. REV. LETT. 84, 3193-3196 (2000).
  40. B. O'Shaughnessy and D. Vavylonis, "Interfacial Reaction Kinetics", EUR. PHYS. J. E 1, 159-177 (2000).
  41. B. O'Shaughnessy and D. Vavylonis, "Reactive Polymer Interfaces: How Reaction Kinetics Depend on Reactivity and Density of Chemical Groups", MACROMOLECULES 32, 1785-1796 (1999).
  42. B. O'Shaughnessy and D. Vavylonis, "Reactions at Polymer Interfaces: Transitions from Chemical to Diffusion-Control and Mixed Order Kinetics", EUROPHYS. LETT. 45, 638-644 (1999).
  43. B. O'Shaughnessy and D. Vavylonis, "Kinetic Regimes and Cross-Over Times in Many-Particle Reacting Systems", EUROPHYS. LETT. 45, 653-658 (1999).
  44. B. O'Shaughnessy and D. Vavylonis, "Reaction Kinetics in Polymer Melts", EUR. PHYS. J. B 6, 363-372 (1998).


  1. T. C. Bidone, H. Tang and D. Vavylonis, "Insights into the mechanics of cytokinetic ring assembly using 3D modeling," Int. Mech. Eng. Congress Expo. 2014;9. pii: V009T12A090
  2. T. Xu, H. Li, T. Shen, N. Ojkic, D. Vavylonis, X. Huang "Extraction and analysis of actin networks based on open active contour models," Proc IEEE Int. Symp. Biomed. Imaging. 2011:1334-1340 (2011).
  3. H. Li, T. Shen, D. Vavylonis, X. Huang, "Actin Filament Segmentation Using Spatiotemporal Active-Surface and Active-Contour Models," Med. Image Comput. Comput. Assist. Interv. 13:86-94 (2010) .
  4. H. Li, T. Shen, D. Vavylonis, X. Huang, "Actin Filament Tracking Based on Particle Filters and Stretching Open Active Contour Models," Med. Image Comput. Comput. Assist. Interv. 12:673-681 (2009)  
  5. H. Li, T. Shen, M. B. Smith, I. Fujiwara, D. Vavylonis, and X. Huang, "Automated Actin Filament Segmentation, Tracking, and Tip Elongation Measurements based on Open Active Contour Models," Proc IEEE Int. Symp. Biomed Imaging. 2009:1302-1305 (2009) .


  1. "How Will Kinetics and Thermodynamics Inform Our Future Efforts to Understand and Build Biological Systems?" CELL SYSTEMS 4:144-146 (2017)