Dimitrios Vavylonis, Professor
Our group develops
theoretical models describing the role of the actin cytoskeleton in cell organization and function. Networks and bundles of actin
filaments spontaneously form subcellular structures with mechanical
integrity that provide cells with shape, generate mechanical forces and
movement by polymerization, and act as tracks for motor proteins. In
collaboration with biologists and computer scientists, we use the
methods of physics to study, analyze, and model the physical properties
of these adaptive biological materials.
Their plasticity underlies the function of the actomyosin contractile
ring during cytokinesis and cell polarization for directional cell
motion and growth.
Dr. Vavylonis received his
doctorate and master's degree in physics from Columbia University and his
bachelor's degree in physics from the University of Athens. He joined Lehigh
from Columbia University and Yale University, following postdoctoral work in
Columbia's department of chemical engineering and Yale's department of
molecular, cellular, and developmental biology.
Our work is currently supported by